METABOLIC AND CLINICAL-RADIOLOGICAL CHANGES IN PATIENTS WITH SYMPTOMATIC EPILEPSYON THE BACKGROUND OF RUPTURED ANEURYSM IN BRAIN
Abstract
The results of the study of metabolic and clinical-radiological changes in patients of two groups with and without symptomatic epilepsy on the background of hemorrhages from ruptured arterial aneurysms are shown. The findings suggest that there is the development of hypoxic nature of violations with the activation of prooxidant reactions in both groups, however, in patients with symptomatic epilepsy was found a significant decrease in antioxidant activity of enzymatic and non-enzymatic cell protection systems with increasing the production of the proinflammatory cytokine TNF-alpha in contrast to the group of patients without epilepsy.
About the Authors
N. I. Nechipurenko
Республиканский научно-практический центр неврологии и нейрохирургии
Belarus
Belarus
R. R. Sidorovich
Республиканский научно-практический центр неврологии и нейрохирургии
Belarus
Belarus
I. D. Pashkovskaya
Республиканский научно-практический центр неврологии и нейрохирургии
Belarus
Belarus
O. L. Zmachynskaya
Республиканский научно-практический центр неврологии и нейрохирургии
Belarus
Belarus
L. A. Vasilevskaya
Республиканский научно-практический центр неврологии и нейрохирургии
Belarus
Belarus
References
1. Литовченко Т.А., Флорикян В.А. // Укр. вестник психоневр. 2014. Т. 22, № 3. С. 139-145.
2. Hunt W.E., Hess R.M. // J. Neurosurg. 1968. Vol. 28. P. 14-19.
3. Drake C.G. // J. Neurosurg. 1988. Vol. 68. P. 985-986.
4. Костюк В.А., Потапович А.И. // Вопр. мед. химии. 1987. № 3. С.115-118.
5. Костюк В.А., Потапович А.И., Ковалева Ж.В. // Вопр. мед. химии. 1990. Т.36, № 2. С. 88-91.
6. Starke R.M. // Curr Neurovasc Res. 2013. Vol. 10 (3). P. 247-255.
7. Chen X.L., Zhang Q., Zhao R. et. al. // Am J Physiol Heart Circ Physiol. 2004. Vol. 286 (3). P. 1001-1007.
Review
For citations:
Nechipurenko N.I., Sidorovich R.R., Pashkovskaya I.D., Zmachynskaya O.L., Vasilevskaya L.A. METABOLIC AND CLINICAL-RADIOLOGICAL CHANGES IN PATIENTS WITH SYMPTOMATIC EPILEPSYON THE BACKGROUND OF RUPTURED ANEURYSM IN BRAIN. Doklady BGUIR. 2016;(7):144-148. (In Russ.)
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