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METHODS of restoration of impaired functions OF BRAIN AFTER THE INTRODUCTION OF STEM CELLS in the Meckel’s space

Abstract

In the series of experiments on Wistar rats ( n = 26) after implantation of 40 thousand mesenchymal stem cells in 50 μl of buffer solution into the Meckel’s space after modeling unilateral or bilateral lesions of the cerebellar cortex it was found better recovery of motor-estimated activity after administered mesenchymal stem cells in animals with unilateral injury which coincided with a more intense movement of mesenchymal stem cells in a region of the brain trauma if MSC was administered to Gasser’s node on the side of the injury.

About the Authors

Y. G. Shanko
РНПЦ неврологии и нейрохирургии
Belarus


Y. P. Stukach
Институт физиологии НАН Беларуси
Belarus


V. A. Kulchitsky
Институт физиологии НАН Беларуси
Belarus


A. L. Tanin
РНПЦ неврологии и нейрохирургии
Belarus


V. V. Kulevas
РНПЦ неврологии и нейрохирургии
Belarus


E. Y. Chernysh
РНПЦ неврологии и нейрохирургии
Belarus


References

1. Flanagan S.R. // Arch. Phys. Med. Rehabil. 2015. Vol. 96. P. 1753-1755.

2. Huang S., Xu L., Sun Y. et. al. // PLoS One. 2016. Vol. 11, № 10. P. e0163131.

3. Feng N., Hao G., Yang F. et. al. // Exp. Ther. Med. 2016. Vol. 11, № 5. P. 1595-1600.


Review

For citations:


Shanko Y.G., Stukach Y.P., Kulchitsky V.A., Tanin A.L., Kulevas V.V., Chernysh E.Y. METHODS of restoration of impaired functions OF BRAIN AFTER THE INTRODUCTION OF STEM CELLS in the Meckel’s space. Doklady BGUIR. 2016;(7):265-269. (In Russ.)

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ISSN 1729-7648 (Print)
ISSN 2708-0382 (Online)