Oxide Films with Built-in Electric Charge for Regulation of Hemostasis Processes
https://doi.org/10.35596/1729-7648-2025-23-1-7-13
Abstract
The formation of films of valve metal oxides of the aluminum, zirconium, titanium, tantalum, niobium series with a thickness of about 100 nm by electrochemical anodization in an electrolyte based on a 1 % aqueous solution of citric acid is considered. The effect of films of anodic oxides of valve metals with a built-in electret charge on the process of blood hemostasis when it contacts the surface of oxide films is studied. It is found that films of oxides with a negative electric charge (oxides of aluminum and zirconium) slow down the process of blood hemostasis, and films of anodic oxides with a positive electric charge (oxides of niobium and tantalum) accelerate it. Recommendations are given for the use of coatings with a negative electric charge as implant coatings to ensure a thromboresistant effect. Positively charged valve metal oxides can be used in wound treatment to stop bleeding.
About the Authors
S. K. Lazarouk
Belarusian State University of Informatics and Radioelectronics
(BSUIR)
Belarus
Belarus
Lazarouk Serguei Konstantinovich, Dr. of Sci. (Phys. and Math.), Professor, Head of the Research Laboratory “Integrated Micro- and Nanosystems” (Lab 4.6)
220013, Minsk, P. Brovki St., 6
O. V. Kupreeva
Belarusian State University of Informatics and Radioelectronics
(BSUIR)
Belarus
Belarus
Researcher at the Lab 4.6
Minsk
L. P. Tomashevich
Belarusian State University of Informatics and Radioelectronics
(BSUIR)
Belarus
Belarus
Electronics Engineer at the Lab 4.6
Minsk
E. A. Utkina
Belarusian State University of Informatics and Radioelectronics
(BSUIR)
Belarus
Belarus
Associate Professor, Leading Researcher at the Research Laboratory “Hybrid Microcircuit Technology” (Lab 4.2)
Minsk
D. V. Zhyhulin
JSC “INTEGRAL” – Manager Holding Company “INTEGRAL”
Belarus
Belarus
Head of the Sector of Physical and Technical Analysis of the “Belmicroanalysis” State Center
Minsk
F. A. Gorbacheu
Belarusian State Medical University (BSMU)
Belarus
Belarus
Associate Professor at the Depart ment of Maxillofacial Surgery
Minsk
A. S. Lastovka
Belarusian State Medical University (BSMU)
Belarus
Belarus
Professor at the Department of Maxillofacial Surgery
Minsk
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Review
For citations:
Lazarouk S.K., Kupreeva O.V., Tomashevich L.P., Utkina E.A., Zhyhulin D.V., Gorbacheu F.A., Lastovka A.S. Oxide Films with Built-in Electric Charge for Regulation of Hemostasis Processes. Doklady BGUIR. 2025;23(1):7-13. (In Russ.) https://doi.org/10.35596/1729-7648-2025-23-1-7-13
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