<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">bsuir</journal-id><journal-title-group><journal-title xml:lang="ru">Доклады БГУИР</journal-title><trans-title-group xml:lang="en"><trans-title>Doklady BGUIR</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1729-7648</issn><issn pub-type="epub">2708-0382</issn><publisher><publisher-name>БГУИР</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">bsuir-1034</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>УГЛЕРОДОСОДЕРЖАЩИЕ ЭКРАНЫ ДЛЯ ЗАЩИТЫ ОРГАНИЗМА ЧЕЛОВЕКА ОТ ЭЛЕКТРОМАГНИТНОГО ИЗЛУЧЕНИЯ</subject></subj-group></article-categories><title-group><article-title>МЕТОД АТОМНО-СИЛОВОЙ МИКРОСКОПИИ В ИССЛЕДОВАНИИ ТРОМБОЦИТОВ ПАЦИЕНТОВ С ТЕРМИНАЛЬНОЙ СТАДИЕЙ ХРОНИЧЕСКОЙ СЕРДЕЧНОЙ НЕДОСТАТОЧНОСТИ</article-title><trans-title-group xml:lang="en"><trans-title>Atomic force microscopy method in the study of platelets of patients with end-stage of chronic heart failure</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кухаренко</surname><given-names>Л. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kukharenko</surname><given-names>L. V.</given-names></name></name-alternatives><email xlink:type="simple">KukharenkoLV@bsmu.by</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чижик</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Chizhik</surname><given-names>S. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дрозд</surname><given-names>Е. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Drozd</surname><given-names>E. S.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гольцев</surname><given-names>М. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Goltsev</surname><given-names>M. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мороз-Водолажская</surname><given-names>Н. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Maroz-Vadalazhskaya</surname><given-names>N. N.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>Белорусский государственный медицинский университет, Республика Беларусь</institution><country>Belarus</country></aff><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>03</day><month>06</month><year>2019</year></pub-date><volume>0</volume><issue>7</issue><fpage>12</fpage><lpage>17</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Кухаренко Л.В., Чижик С.А., Дрозд Е.С., Гольцев М.В., Мороз-Водолажская Н.Н., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Кухаренко Л.В., Чижик С.А., Дрозд Е.С., Гольцев М.В., Мороз-Водолажская Н.Н.</copyright-holder><copyright-holder xml:lang="en">Kukharenko L.V., Chizhik S.A., Drozd E.S., Goltsev M.V., Maroz-Vadalazhskaya N.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://doklady.bsuir.by/jour/article/view/1034">https://doklady.bsuir.by/jour/article/view/1034</self-uri><abstract><p>Методом атомно-силовой микроскопии производилась оценка внутрисосудистой активации тромбоцитов и определялись локальный модуль упругости, адгезия, жесткость мембраны тромбоцитов у пациентов с терминальной стадией хронической сердечной недостаточности с использованием имплантируемого двухжелудочкового вспомогательного сердца на этапах до операции и интраоперационно: до введения гепарина, после введения гепарина, после нейтрализации гепарина протамином.</p></abstract><trans-abstract xml:lang="en"><p>Atomic force microscopy was used to estimate the intravascular platelet activation and determine local elastic modulus, adhesion and stiffness of the platelets membrane in patients with end-stage of chronic heart failure with heart ventricle implantation before surgery and intrasurgical: before the heparin injection, after the heparin injection and after neutralization of heparin with protamine.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>атомно-силовая микроскопия</kwd><kwd>тромбоциты</kwd><kwd>терминальная стадия хронической сердечной недостаточности</kwd></kwd-group><kwd-group xml:lang="en"><kwd>atomic force microscopy</kwd><kwd>platelets</kwd><kwd>end-stage of chronic heart failure</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Imaging modes of atomic force microscopy for application in molecular and cell biology / Y.F. Dufrene [et al.] // Nature Nanotechnology. 2017. Vol. 12. P. 295-307. Measuring the viscoelastic properties of human platelets with the atomic force microscope / M. Radmacher [et al.] // Biophys. J. 1996. P. 556-567. Toward correlating structure and mechanics of platelets / S. Sorrentino [et al.] // Cell Adhesion and Migration. 2016. Vol. 10. P. 568-575.</mixed-citation><mixed-citation xml:lang="en">Imaging modes of atomic force microscopy for application in molecular and cell biology / Y.F. Dufrene [et al.] // Nature Nanotechnology. 2017. Vol. 12. P. 295-307. Measuring the viscoelastic properties of human platelets with the atomic force microscope / M. Radmacher [et al.] // Biophys. J. 1996. P. 556-567. Toward correlating structure and mechanics of platelets / S. Sorrentino [et al.] // Cell Adhesion and Migration. 2016. Vol. 10. P. 568-575.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
